===== The main topics ===== **Section 1.** Machine Learning in Fundamental Physics * Machine learning methods in particle astrophysics and high energy physics. * Fast event generators based on machine learning for simulation of physics phenomena. * Multi-messenger data analysis of experimental data. * Application machine learning for data analysis in megascience facilities. **Section 2.** Machine Learning for Environmental Sciences * Climate analysis, retrospective analysis and projection * Statistical modeling of the ocean and atmosphere on various temporal and spatial scales * Environmental monitoring: remote sensing, instrumental monitoring, observations, monitoring networks **Section 3.** Machine Learning in Natural Sciences * Biology and bioinformatics. * Engineering sciences. * Modern Machine Learning Methods **The conference will feature:** * invited presentations – 30 minutes, * regular presentations – 15 minutes,